Alexander Hofmann - AG Groth

The genome of Arabidopsis contains over 600 sequences encoding receptor-like kinases (RLKs), thereby making up almost 2,5% of the complete proteome. As signal receptors and transducers receptor-like kinases are involved in numerous pathways and cascades including pathogen sensing, plant development and hormone response. ERECTA and its two homologs have been shown to regulate the differentiation of stomata cells along many other crucial developmental processes. While extensive genetic studies have been conducted, little is known about the biochemical features of ERECTA, its homologs and putative interaction partners

In my project I want to address physiological as well as structural questions of the RERECTA and ERECTA-like proteins and their interaction partners. 

Starting date: 02.06.2014 / PhD student

Thesis committee members: Georg Groth, Rüdiger Simon

Mini Academic CV:

  •  2014: Master of Science in Biology, Martin-Luther-University Halle/Wittenberg
    • Thesis: “Enrichment and analysis of native receptor complexes of the twin arginine translocase from Arabidopsis thaliana, Spinacia oleracea and Pisum sativum
  • 2011: Bachelor of Science in Biology, Martin-Luther-University Halle/Wittenberg
    • Thesis: “Expression of the putative cation importers CorA1, CorA2, CorA3 and PitA from Cupriavidus metallidurans

Publications:

Bisson MM, Kessenbrock M, Müller L, Hofmann A, Schmitz F, Cristescu SM, Groth G (2016) Peptides interfering with protein-protein interactions in the ethylene signaling pathway delay tomato fruit ripening. Sci Rep Aug 1;6:30634.undefined doi:1038/srep30634.

Photo of Alexander  Hofmann

Alexander Hofmann M.Sc.

Building: 26.02.01
Floor/Room: 74
Phone +49 211 81-13722
Responsible for the content: E-MailDr. Petra Fackendahl