Daniela Lichtblau - AG Bauer

Interactions and functions of the transcription factor network for iron-regulated           responses    

Iron (Fe) is an essential micronutrient for plants as well as animals. According to the World Health Organization, the lack of iron is one of the most common nutrient deficiencies in human beings. This problem becomes even more severe with the raising world population. Since plants are the main source for humans iron uptake (especially staple crops like maize, rice or wheat), the so called biofortification tends to improve the food quality by increasing the iron content of staple crops.

Because of the strong requirement for Fe on one hand and the Fe-toxicity on the other hand, a very sensitive fine-tuned mechanism (up- and downregulation) of iron deficiency response genes is needed. To cope with changing environmental conditions the iron uptake system and homeostasis of plants is controlled by a complex network of different transcription factors and other types of proteins. It might be possible that the known transcription factors which form hetero- and homodimers among each other show a distinct hierachial cluster in order to regulate the expression of downstream iron response components. This also raises the question whether there are more yet unknown factors involved in initiating and maintaining the iron deficiency response. The aim of this work is to shed light on the hierarchy of transcription factors and thereby maybe find knew components and perhaps get clues about iron deficiency signals.

Starting date: 01.10.2014 / PhD student

 

Thesis committee members: Petra Bauer, Peter Westhoff

 

Mini Academic CV: 

  • 2014: Master of Science in Biology, Heinrich-Heine-Universität Düsseldorf 
    • Title: “Wurzelarchitektur von Maislininen in Abhängigkeit von der Nitratzufuhr”
  • 2011: Bachelor of Science in Biology, Heinrich-Heine-Universität Düsseldorf
    • Title: “Analyse quantitativer Wurzelmerkmale unter Trockenstress und Stickstoffmangel”

 

 

Photo of Daniela  Lichtblau

Daniela Lichtblau

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